VRG Therapeutics
VRG Therapeutics
Startup
REGULAR MEMBER
REGULAR MEMBER
Description
VRG Therapeutics leverages its AI‑driven, end‑to‑end AI‑MPRO platform to develop novel miniprotein therapeutics to challenging targets such as ion channels and complex multi‑protein interfaces. AI-MPRO enables efficient progression from discovery to preclinical in vitro and in vivo proof‑of‑concept by integrating de novo protein design with rapid in silico–experimental iteration. This approach generates compact, highly optimized, first-in-class or best‑in‑class therapeutic candidates for targets traditionally considered intractable. VRG's lead asset is a Kv1.3 inhibitor with unprecedented potency and selectivity. This project is in preclinical development for chronic inflammatory diseases.
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