MEGAPharma Ltd.

The MEGAPharma Ltd. is a scientific and marketing organization with high potential at different field of pharmaceutical business.

The management of our company has a broad expertise in the different field of pharmaceutical business.
The list of the scientific fields which MEGAPharma have experts in:

Biochemistry:

1. Receptor binding experiments.
2. Measurements in different enzyme systems.
3. Studies on transport systems (at uptake, release, and compartment levels)
4. Determination of biological active components as neurotransmitters, hormones and its metabolites

Pharmacology:

1. Studies on isolated organs
Preparations: Isolated vessels
Perfused arterial segments
Perfused organs
Non-vascular preparations
2. Measurement of released compounds (by different methods)
Fields: Ion transports and neurotransmissions
Testing of vasoactive agents
Measurement of force/shortening
3. Testing of actions of smoke (cigarette) and evaporates.
With special equipment

Pharmacokinetic and metabolism:

1. Determination of the metabolic balance of potential drugs, using positionally labeled compounds (including labeling)
2. Pharmacokinetic studies, using radio labeled compounds (absorption, distribution, binding elimination).
3. Distribution of drugs in mice, using whole body autoradiography, with computer image semiquantitative evaluation.
4. Study of the enterohepatic cycle of drugs.
5. In vitro and in vivo studies on the biotransformation of potential drugs
6. Adaptation of validated HPLC and GC techniques for Human Phase I. Studies, Bioequivalency Studies.
7. Absorption of substances from transdermal patches in human or in domestic pigs.
8. The most frequently used laboratory animals mice, rats, guinea pigs, nude guinea pigs, beagle dogs, Ucatan pigs.
9. Toxicokinetic studies

Pharmaceutical formulations:

1. Transdermal delivery systems:
-Silicone patches
-Liposomes
-Liquid crystal systems
2. Creams and ointments
3. Tablets, dragée

Clinical studies:

1. Organization of Bioequivalency Studies
2. Phase II and III studies
3. Organization of PET studies
4. Organization of different clinical trials, and combined with laboratory determinations.

Management works:

1. Management of drug filing in Hungary
2. Representation at OGYI ( Hungarian Health Authority)
3.Expert reports (Chemical, Pharmaceutical, Preclinical, Clinical)
4. Organization of pharmaceutical products export and import.
5. Developing of a company strategy and profile in science and marketing.
6. Consultancy in privatization, business planning and company evaluation.
7. Market analysis, marketing planning, product evaluation and profiling in Hungary and in the ex-Comecon countries.
8. Organization of scientific meetings, training courses, business- or study -tours in Hungary.

Other: Participating in improving different medical plants

http://www.megapharma.hu

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